Adaptive Deep Brain Stimulation (aDBS) is an advanced form of deep brain stimulation that uses closed-loop technology to deliver real-time adjustments in electrical stimulation based on the patient’s neural activity.
aDBS addresses the limitations of traditional DBS by providing more precise and adaptive treatment for neurological conditions like Parkinson's disease, essential tremor, and obsessive-compulsive disorder (OCD).
The system consists of sensing electrodes that monitor specific biomarker oscillations, such as abnormal neuronal firing patterns. When these patterns are detected, a pulse generator modulates the stimulation to correct them without constant, continuous delivery, thereby optimizing both symptom control and battery life.
Manufacturing involves creating implantable devices with high-precision electrodes and pulse generators. Materials must be biocompatible and capable of long-term stability.
The build process includes designing the hardware components, integrating sensing and stimulation functionalities, and ensuring reliable wireless communication between the implanted device and external programming interfaces.
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