Synthetic Biology Applications in Medicine

Synthetic biology applications in medicine leverage advanced biotechnological techniques to edit genes precisely and deliver drugs directly to target cells.

Challenges in precise genetic modification and targeted drug delivery in medical treatments, including off-target effects and limited efficacy.

Using advanced CRISPR tools, synthetic biology allows for highly targeted gene editing and the creation of engineered biological systems that can be used for drug delivery.

• CRISPR-Cas9
• mRNA
• plasmids
• lentiviruses

Involves the design and construction of biological parts, devices, and systems using standard and semi-standard components.

Design, build, test, and learn (DBTL) cycles are used to iteratively develop synthetic biology constructs for medical applications.

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CRISPR

Clustered Regularly Interspaced Short Palindromic Repeats, a genetic engineering tool used for precise gene editing.

mRNA

Messenger RNA, a molecule that carries instructions from DNA to the ribosomes in cells, where proteins are synthesized.

plasmids

Small circular DNA molecules within bacteria that can replicate independently of the bacterial chromosome, often used as vectors in genetic engineering.

lentiviruses

A type of retrovirus capable of infecting both dividing and non-dividing cells, commonly used for gene delivery in medical applications.

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